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What are Tiopronin
Delayed-Release Tablets?

This is a prescription medication used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type of kidney stones (cystine) in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.

Tiopronin Delayed-Release Tablets are the only authorized generic with FDA approval available exclusively through MyCare SolutionsTM.

FIND OUT MORE

Dosage forms and strengths

100 mg delayed-release tablet

300 mg delayed-release tablet

Tablets shown not actual size.

What are Tiopronin
Delayed-Release Tablets?

This is a prescription medication used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type of kidney stones (cystine) in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.

Tiopronin Delayed-Release Tablets are the only authorized generic with FDA approval available exclusively through MyCare SolutionsTM.

FIND OUT MORE

100 mg delayed-release tablet

Dosage forms and strengths

300 mg delayed-release tablet

Tablets shown not actual size.

How does it work?

Tiopronin works by chemically binding to cystine in the urine and making it dissolve more easily so that stones become less likely to form.

Tiopronin Delayed-Release Tablets are proven to greatly reduce or eliminate the cystine stone formation, but patients must remain on conservative therapy because they all work together.

Conservative therapies include:

  1. Drink enough fluids, mainly water, around the clock to ensure the patient excretes 2.5 Liters (L) or more of urine per day (3 liters is preferred). Please think about how much that is. That is 2 ¼ to 2 ½ large soda bottles worth per day. Be aware our bodies lose water through sweating and respiration (i.e., our breathing) and these losses don’t make their way into our urine output.
  2. Patients must reduce their total sodium intake to less than or equal to 2,300 mg per day. Note: the typical American diet is 3,400 mg (or 3.4 grams) per day.
  3. Reduce animal protein in their diet, especially proteins high in methionine (an amino acid). High-methionine foods include turkey, beef, fish, pork, tofu, milk, cheese, nuts, beans, and whole grains like quinoa. These should be minimized or avoided in the diet.

How do I take it?

  • Follow instructions from your heathcare professional for dosing.
  • General guidelines for dosing –
    • For children weighing 20 kg and greater, the tiopronin dose is 15-40 mg/kg/day in 3 divided doses at the same times each day.
  • Tiopronin Delayed-Release Tablets can be given with or without food.

Please click here for Prescribing Information including additional Important Safety Information.

Proudly manufactured in the USA

This material is intended to provide basic information and is not medical advice. All medical advice, diagnosis, and treatment should be obtained from your physician. The product information provided in this site is intended for residents of the United States.

Copyright © 2025 BioComp Pharma, Inc. All rights reserved.

San Antonio, TX 78230

Proudly manufactured in the USA

This material is intended to provide basic information and is not medical advice. All medical advice, diagnosis, and treatment should be obtained from your physician. The product information provided in this site is intended for residents of the United States.

Copyright © 2025 BioComp Pharma, Inc. All rights reserved.

San Antonio, TX 78230
Important Safety Information Expand + Minimize -

What are Tiopronin Delayed-Release Tablets?
Tiopronin Delayed-Release Tablets are a prescription medication. It is used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type (cystine) of kidney stones in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.

Who should not take Tiopronin Delayed-Release Tablets?
Tiopronin Delayed-Release Tablets should not be taken if you:

  • Are allergic to Tiopronin Delayed-Release Tablets, or any of the ingredients in Tiopronin Delayed-Release Tablets.

What should I tell my doctor before taking Tiopronin Delayed-Release Tablets?
Tiopronin Delayed-Release Tablets may not be right for you. Before taking Tiopronin Delayed-Release Tablets, tell your doctor about:

  • all health conditions you may have and any medications you may be taking
  • if you are pregnant or plan to become pregnant
  • if you are breastfeeding or plan to breastfeed

What should I avoid while taking Tiopronin Delayed-Release Tablets?
You should avoid drinking alcohol 2 hours before and 3 hours after taking Tiopronin Delayed-Release Tablets.

What are possible side effects of Tiopronin Delayed-Release Tablets?
Serious Side Effects: Tiopronin Delayed-Release Tablets can cause proteinuria (high amounts of protein in urine), including serious kidney problems, and hypersensitivity reactions (including fever, rash, joint pain and enlarged or swollen lymph nodes).
Most Common Side Effects: Nausea, diarrhea or soft stools, sores in the mouth, rash, fatigue, fever, muscle or joint pain, high amounts of protein in urine, vomiting.

These are not all the possible side effects of Tiopronin Delayed-Release Tablets. Call your doctor for medical advice about side effects.

You may report negative side effects to BioComp Pharma, Inc. at 1-866-762-2365, or to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please click here for full Prescribing Information including additional Important Safety Information.

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