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What are Tiopronin
Delayed-Release Tablets?

This is a prescription medication used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type of kidney stones (cystine) in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.

Tiopronin Delayed-Release Tablets are the only authorized generic with FDA approval available exclusively through MyCare SolutionsTM.

FIND OUT MORE

Dosage forms and strengths

100 mg delayed-release tablet

300 mg delayed-release tablet

Tablets shown not actual size.

What are Tiopronin
Delayed-Release Tablets?

This is a prescription medication used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type of kidney stones (cystine) in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.

Tiopronin Delayed-Release Tablets are the only authorized generic with FDA approval available exclusively through MyCare SolutionsTM.

FIND OUT MORE

100 mg delayed-release tablet

Dosage forms and strengths

300 mg delayed-release tablet

Tablets shown not actual size.

How does it work?

Tiopronin works by chemically binding to cystine in the urine and making it dissolve more easily so that stones become less likely to form.

Tiopronin Delayed-Release Tablets are proven to greatly reduce or eliminate the cystine stone formation, but patients must remain on conservative therapy because they all work together.

Conservative therapies include:

  1. Drink enough fluids, mainly water, around the clock to ensure the patient excretes 2.5 Liters (L) or more of urine per day (3 liters is preferred). Please think about how much that is. That is 2 ¼ to 2 ½ large soda bottles worth per day. Be aware our bodies lose water through sweating and respiration (i.e., our breathing) and these losses don’t make their way into our urine output.
  2. Patients must reduce their total sodium intake to less than or equal to 2,300 mg per day. Note: the typical American diet is 3,400 mg (or 3.4 grams) per day.
  3. Reduce animal protein in their diet, especially proteins high in methionine (an amino acid). High-methionine foods include turkey, beef, fish, pork, tofu, milk, cheese, nuts, beans, and whole grains like quinoa. These should be minimized or avoided in the diet.

How do I take it?

  • Follow instructions from your heathcare professional for dosing.
  • General guidelines for dosing –
    • For children weighing 20 kg and greater, the tiopronin dose is 15-40 mg/kg/day in 3 divided doses at the same times each day.
  • Tiopronin Delayed-Release Tablets can be given with or without food.

Please click here for Prescribing Information including additional Important Safety Information.

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The information in the following section is intended for US Healthcare Professionals only.
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