FAQs

Tiopronin works by chemically binding to cystine in the urine and making it dissolve more easily so that stones become less likely to form.

Conservative therapy includes:

1. Drinking enough fluids, mainly water, around the clock to ensure the patient excretes 2.5 Liters (L) or more of urine per day (3 liters is preferred). Please think about how much that is. That is 2 ¼ to 2 ½ large soda bottles worth per day. Be aware our bodies lose water through sweating and respiration (i.e., our breathing) and these losses don’t make their way into our urine output.
2. Reducing total sodium intake to less than or equal to 2,300 mg per day. Note: the typical American diet is 3,400 mg (or 3.4 grams) per day.
3. Reducing animal protein in their diet, especially proteins high in methionine (an amino acid). High-methionine foods include turkey, beef, fish, pork, tofu, milk, cheese, nuts, beans, and whole grains like quinoa. These should be minimized or avoided in the diet.

Tiopronin Delayed-Release Tablets should not be taken if you are allergic to Tiopronin Delayed-Release Tablets, or any of the ingredients in Tiopronin Delayed-Release Tablets.

• all health conditions you may have and any medications you may be taking
• if you are pregnant or plan to become pregnant
• if you are breastfeeding or plan to breastfeed

You should avoid drinking alcohol 2 hours before and 3 hours after taking Tiopronin Delayed-Release Tablets.

Serious Side Effects: Tiopronin Delayed-Release tablets can cause proteinuria (high amounts of protein in urine), including serious kidney problems, and hypersensitivity reactions (including fever, rash, joint pain and enlarged or swollen lymph nodes).

Most Common Side Effects: Nausea, diarrhea or soft stools, sores in the mouth, rash, fatigue, fever, muscle or joint pain, high amounts of protein in urine, vomiting.

These are not all the possible side effects of Tiopronin Delayed-Release tablets. Call your doctor for medical advice about side effects.

You may report negative side effects to BioComp Pharma, Inc. at 1-800-298-1087, or to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.